CD32 (Phospho-Tyr292) Antibody MBS9412345 from MyBioSource.com

Description

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.Stuart S.G., EMBO J. 8:3657-3666(1989).Brooks D.G., J. Exp. Med. 170:1369-1385(1989).Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990)

Product Specs
ItemCD32 (Phospho-Tyr292) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS9412345
Quantity0.05 ml
ApplicationsWestern Blot (WB)
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
FormatRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
PurityAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
ReactivityHuman
TargetCD32
Molecular Weight33,450 Da
HostRabbit
ImmunogenThe antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292
NCBI Full Gene NameFc fragment of IgG, low affinity IIb, receptor (CD32)
NCBI Gene AliasesCD32, IGFR2, FCGR2, FCG2, CD32B
ClonalityPolyclonal